Hormone Replacement Therapy

Take control of your energy & performance with our Bio-Optimized Protocol. Physician-supervised bioidentical hormone optimization for men and women.

Medical consultation at Zen Regenerative Wellness

The Hormonal Decline

Beginning in your early-to-mid 30s, your body's production of key hormones begins a steady, progressive decline. For men, testosterone drops approximately 1-2% per year after age 30. By 50, many men have lost 30-50% of their peak levels. For women, estrogen, progesterone, and testosterone all decline in the late 30s, accelerating through perimenopause and plummeting during menopause.

These aren't just "sex hormones." Testosterone, estrogen, progesterone, DHEA, and thyroid hormones regulate virtually every system in your body — and when they decline, the effects are widespread and cumulative:

Persistent fatigue & low energy
Brain fog & declining mental clarity
Muscle loss & stubborn weight gain
Low libido & sexual dysfunction
Mood swings, anxiety & irritability
Poor sleep quality & insomnia
Thinning hair & accelerated aging
Joint pain & decreased bone density
Weakened immune function

Our HRT Process

STEP 01

Comprehensive Labs

Full hormonal panel including testosterone (free & total), estrogen, progesterone, DHEA-S, thyroid (TSH, free T3/T4), cortisol, SHBG, and metabolic markers.

STEP 02

Personalized Protocol

Your physician designs a customized HRT plan based on labs, symptoms, health history, and goals — not a one-size-fits-all prescription.

STEP 03

Ongoing Monitoring

Regular lab checks (typically every 8-12 weeks initially, then quarterly) to optimize dosing and ensure safety. Direct physician access throughout.

Explore Your Protocol

The Zen Difference

Hormone therapy is not one-size-fits-all. A "normal" lab range and an "optimal" lab range are very different things. Conventional medicine often tells patients their levels are "normal" when they're actually at the bottom of the reference range — technically within bounds but far from where they need to be for vitality and function.

At Zen, we don't treat lab ranges — we treat patients. Every protocol is designed by Dr. Kris Shewmake based on your unique labs, symptoms, goals, and lifestyle. We use only bioidentical hormones — molecules that are structurally identical to what your body naturally produces — sourced from licensed compounding pharmacies.

We monitor aggressively, adjust precisely, and maintain direct physician access throughout your optimization journey. This is not a testosterone mill or a cookie-cutter protocol. This is precision medicine.

HRT Pricing: Starting at $250/month (Female) | $450/month (Male) — Includes physician oversight, lab monitoring, and medication management

From the Regen Blog

Deeper Reads on Hormone Therapy

Honest, in-depth perspectives from the Zen clinical team — written for patients who want the science behind every recommendation.

Hormone Therapy

Bioidentical vs. Synthetic Hormones: Why the Distinction Matters

Not all hormone replacement is created equal. Dr. Shewmake explains the critical molecular differences between bioidentical and synthetic hormones — and why one carries dramatically different risks.

Kris Shewmake, MD

9 min read

Hormone Therapy

Hormone Optimization: What Every Man and Woman Over 35 Should Know

Hormones control everything from energy and mood to body composition and libido. When they decline — and they will — here's how we restore them safely.

Kris Shewmake, MD

12 min read

Lab Testing

Lab Testing Decoded: What Your Numbers Actually Mean (and What Your Doctor Isn't Telling You)

That "normal" on your lab results might be far from optimal. Dr. Shewmake explains the difference between reference ranges and functional ranges — and why it changes everything.

Kris Shewmake, MD

11 min read

Browse the Full Regen Blog

Have questions about hormone therapy? Visit our FAQ page

Reclaim Your Vitality

Schedule your hormone evaluation and comprehensive lab work today.